Eggs got blamed. Look what was next to them.
People say: “Eggs are bad for your heart” We read the study.
Meta-analysis of cohort studies. 215,618 people. up to 32 years of follow-up (NHS 1980-2012, NHS II 1991-2013, HPFS 1986-2012), >5.54 million person-years.
Many studies, added up. People were watched, not told what to do. A clue, not proof.
Who: US health professionals: 83,349 women (Nurses' Health Study), 90,214 women (NHS II), 42,055 men (Health Professionals Follow-Up Study), free of cardiovascular disease, type 2 diabetes and cancer at baseline. Meta-analysis: 28 studies, 1,720,108 participants (US, Europe, Asia)
- Extra risk: 1 egg a daynone3 US cohorts, adjusted
- Extra risk: 1.7M peoplenonemeta-analysis
- Swap egg → processed meat+15%statistical model
Up to 1 egg a day: not linked to heart disease, after adjusting for diet and lifestyle
Type 2 diabetes: possibly higher risk.
More to know, from our read of the paper:
- Observational (cohorts + meta-analysis of cohorts): association, not causation. 'Not associated' does not prove eggs are protective or 'healthy'
- Egg intake self-reported on food frequency questionnaires (whole eggs with yolk; eggs in baked goods, liquid eggs and egg whites excluded from the main exposure)
- Very few people ate a lot of eggs: in 1998-99 only 1.24% ate at least 1 egg/day and 0.20% at least 2/day; most ate 1 to <5 eggs/week. The authors say this low intake should be taken into account
- Blood cholesterol was NOT the outcome; the paper measured heart attacks, coronary deaths and strokes, not whether eggs raise LDL
- Cohorts are US health professionals (mostly white nurses/health workers), possibly not generalisable (stated by the authors)
Up to 1 egg a day: no link found.
- Up to 1 a day: no linkFew ate more, so higher amounts are less certain.
- Watch what's next to themBacon & processed meat: the swap linked to higher risk.
- Diabetes? Ask your doctorMore eggs pointed to higher risk; evidence mixed.
3 US cohorts (215,618 health professionals, up to 32 years) + a meta-analysis of 1.7 million people: up to one egg a day was not linked to heart disease after adjusting for diet and lifestyle. Not linked ≠ proven healthy. Possible exception: people with type 2 diabetes. Food was self-reported.
Drouin-Chartier et al. (2020). Egg consumption and risk of cardiovascular disease: three large prospective US cohort studies, systematic review, and updated meta-analysis. BMJ.
Design: Meta-analysis of cohort studies · three prospective cohort studies + systematic review and meta-analysis of prospective cohort studies (observational: linked, not proven)
DOI: 10.1136/bmj.m513
Goals:
We read the abstract and the full text of this paper and checked every number on this page against it (18 facts, checked on 2026-10-01). The study design is named above. Cohort and other observational studies are described as linked, not proven. Found an error? Email theis@onestudyaday.com.
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