An online therapy program helped students. Half its users spent under twenty minutes.

People say: “Can an online program ease anxiety or depression?” We read the study.

What they did

Randomised controlled trial (RCT). 6,205 people. 6-month access to the program; follow-ups at 6 weeks, 6 months and 2 years (recruited Oct 2019 - Nov 2021, data collection completed Oct 2023).

A trial. Chance decided who did what.

Who: Undergraduates aged 18+ at 26 US colleges and universities who screened (self-report) at clinical level (4,538) or high risk (1,667) for generalized anxiety, social anxiety, panic, depression and/or eating disorders (not anorexia), not in psychotherapy in the past month, owning a smartphone; mean age 20.2, 26.5% male; 39,194 students answered the screen

What they found
  • Had a disorder, 6 mo-4.9 pts56% vs 61%
  • Had a disorder, 2 yrs-3.8 pts55.5% vs 59.3%
  • Got any help, 6 mo74 vs 30% of students
The catch

More to know, from our read of the paper:

  • Disorder status is based on validated self-report questionnaires with clinical cut-offs, not clinician interviews: say 'by their own answers' / 'self-reported'
  • The comparison is referral to campus care, not in-person therapy; both groups also got screening and feedback, and both groups improved over time
  • At 6 weeks the benefit was only significant in students with clinical-level symptoms, not in the high-risk group; by 6 months and 2 years the full sample benefited
  • Symptom-score effects are small (between-group d about 0.06-0.19). Panic symptoms: no difference at any time. Generalized anxiety: only at 6 weeks. Eating-disorder and social-anxiety symptoms: not at 2 years. Depression: at all three times
  • Engagement was low: among the 2,308 who used the program, median 4 visits and median 18.0 minutes in total (mean 98.8); on average 2.4 modules of 6-8
The verdict

Small but lasting gains for US college students.

One thing to try
  1. Coached online CBT is an optionHere it beat a referral to campus care.
In short

In this randomized trial at 26 US colleges, 6,205 students with signs of anxiety, depression or an eating disorder (by their own questionnaire answers) got either a coached online CBT program or a referral to campus care. After 6 months, 56% vs 61% still had at least one disorder; after 2 years, 55.5% vs 59.3%. 74% started the program, while 30% of the referral group reported therapy or new medication. Half of the program's users spent 18 minutes or less in it, and panic symptoms did not change more than in the other group.

The video
The paper

Newman MG, Fitzsimmons-Craft EE, Baik SY, Zainal NH, Calderon A, Rackoff GN, Firebaugh ML, Rojas-Ashe E, Leykin Y, Lew D, Eisenberg D, Taylor CB, Wilfley DE (2026). Population-based RCT of a digital cognitive-behavioural guided self-help intervention for anxiety, depression and eating disorders in college students. Nature Human Behaviour.

Design: Randomised controlled trial (RCT) · pragmatic effectiveness randomized controlled superiority trial (NCT04162847, analyses preregistered), randomised within each college; not blinded; all randomised participants analysed with multiple imputation

DOI: 10.1038/s41562-026-02454-z

Goals:

How we checked

We read the abstract and the full text of this paper and checked every number on this page against it (16 facts, checked on 2026-10-29). The study design is named above. Cohort and other observational studies are described as linked, not proven. Found an error? Email theis@onestudyaday.com.

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