Lifting weights was linked to fewer heart attacks. Not fewer strokes.
People say: “Heart health is all about cardio” We read the study.
Cohort study. 117,025 people. mean follow-up 14.5 years (1,630,964 person-years); NHS 2002-2020, NHS II 2003-2017; up to five repeated assessments of physical activity.
People were watched for years. Nobody was told what to do. A clue, not proof.
Who: US female registered nurses free of MI, CABG, angina, stroke and cancer at baseline: 45,669 from NHS (mean age 66.8) and 71,356 from NHS II (mean age 48.1); ~97.5% White
- Heart & stroke events-20%2+ hours a week
- Heart attacks-44%2+ hours a week
- Fewer strokesnoneno clear change
More to know, from our read of the paper:
- Observational cohort: linked, not proven. Authors: residual confounding by healthy-user traits (health consciousness, access to care, social support) cannot be ruled out
- Resistance training self-reported (hours/week for arms and legs, summed); no information on type, intensity or supervision
- All participants were nurses, ~97.5% White: may not apply to other populations
- Main model (Model 3) adjusts for aerobic activity, smoking, alcohol, diet, calories, aspirin, menopause, family history, race; it does NOT adjust for BMI or diabetes/hypertension/cholesterol (treated as mediators). With BMI: HR 0.83 (0.72-0.96); plus cardiometabolic conditions: HR 0.86 (0.75-0.98)
- Among women already meeting aerobic guidelines, the major-CVD association was marginal (HR 0.86, 0.73-1.01); only MI stayed clearly lower (HR 0.55)
Weights linked to fewer heart attacks. Not strokes.
- Do bothCardio + weights + little TV: lowest risk.
Researchers followed 117,025 US nurses for about 14.5 years. Women who reported 2 or more hours of strength training a week had a 20% lower risk of heart attack, stroke, bypass or stent combined, and 44% lower risk of heart attack alone, than women who did none. Stroke showed no clear change. Women who did cardio, lifted weights and watched under 2 hours of TV a day had the lowest risk. This is an observational study: linked, not proven.
Zhang T, Zhang Y, Lee DH, Rezende LFM, Wang X, Zheng C, Giovannucci E (2026). Resistance Training, Aerobic Activity, Television Viewing, and Risk of Major Cardiovascular Events in U.S. Women. Journal of the American College of Cardiology.
Design: Cohort study · prospective cohort study (two pooled cohorts: Nurses' Health Study and Nurses' Health Study II), repeated self-reported exposure every ~4 years, time-varying cumulative averages, 2-year lag; Cox models (linked, not proven)
DOI: 10.1016/j.jacc.2026.04.036
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